Acyl transfer from phosphocholine lipids to melittin

Pridmore, Catherine J.; Mosely, Jackie A.; Rodger, Alison; Sanderson, John M.

doi:10.1039/c0cc04677a

Acyl transfer from phosphocholine lipids to melittin

Pridmore, Catherine J.; Mosely, Jackie A.; Rodger, Alison; Sanderson, John M.

Authors

Catherine J. Pridmore

Jackie A. Mosely

Alison Rodger

Dr John Sanderson j.m.sanderson@durham.ac.uk
Associate Professor

Abstract

Transfer of fatty acyl groups from membrane phospholipids to melittin, a commonly studied membrane-active peptide, has been observed to occur over extended time periods. Transfer can be detected after 1–2 days and selectively targets amino groups at the N-terminal end of the peptide.

Citation

Pridmore, C. J., Mosely, J. A., Rodger, A., & Sanderson, J. M. (2011). Acyl transfer from phosphocholine lipids to melittin. Chemical Communications, 47(5), 1422-1424. https://doi.org/10.1039/c0cc04677a

Journal Article Type	Article
Publication Date	Feb 1, 2011
Deposit Date	Feb 9, 2011
Publicly Available Date	Jan 3, 2012
Journal	Chemical Communications
Print ISSN	1359-7345
Electronic ISSN	1364-548X
Publisher	Royal Society of Chemistry
Peer Reviewed	Peer Reviewed
Volume	47
Issue	5
Pages	1422-1424
DOI	https://doi.org/10.1039/c0cc04677a
Keywords	Melittin, Membrane, Peptide, Acylation.