Rae, Bruce and Muir, Keith R. and Gong, Zheng and McKendry, Jonathan and Girkin, John M. and Gu, Erdan and Renshaw, David and Dawson, Martin D. and Henderson, Robert (2009) 'A CMOS time-resolved fluorescence lifetime analysis micro-system.', Sensors., 9 (11). pp. 9255-9274.
We describe a CMOS-based micro-system for time-resolved fluorescence lifetime analysis. It comprises a 16 × 4 array of single-photon avalanche diodes (SPADs) fabricated in 0.35 μm high-voltage CMOS technology with in-pixel time-gated photon counting circuitry and a second device incorporating an 8 × 8 AlInGaN blue micro-pixellated light-emitting diode (micro-LED) array bump-bonded to an equivalent array of LED drivers realized in a standard low-voltage 0.35 μm CMOS technology, capable of producing excitation pulses with a width of 777 ps (FWHM). This system replaces instrumentation based on lasers, photomultiplier tubes, bulk optics and discrete electronics with a PC-based micro-system. Demonstrator lifetime measurements of colloidal quantum dot and Rhodamine samples are presented.
|Additional Information:||This article belongs to the Special Issue Delft Workshop 2008-2009—Sensors and Imagers: a VLSI Perspective.|
|Full text:||(VoR) Version of Record|
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|Publisher Web site:||http://dx.doi.org/10.3390/s91109255|
|Date accepted:||No date available|
|Date deposited:||08 June 2012|
|Date of first online publication:||November 2009|
|Date first made open access:||No date available|
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